1852 - Studebaker Brothers wagon company, precursor of the automobile manufacturer, is established
1857 - The National Deaf Mute College (later renamed Gallaudet University) is established in Washington, DC becoming the first school for the advanced education of the deaf.
... at the South Pole, first to navigate the Northwest Passage in a single ship
Roy Chapman Andrews, (1884-1960), US explorer
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Vasco Nunez de Balboa, (c. 1475-1519), ...