The late Tokugawa shogunate or last shogun (幕末; Bakumatsu) is the period between 1853 and 1867 during which Japan ended its isolationist foreign policy and modernized from a feudal shogunate to the Meiji government. It is at end of Edo period and preceeded by Meiji era.
... to keep them warm or fed. After twelve years of ministering to the patients at the leper colony (see Kalawao County, Hawaii), he contracted the disease, from which h ...