The late Tokugawa shogunate or last shogun (幕末; Bakumatsu) is the period between 1853 and 1867 during which Japan ended its isolationist foreign policy and modernized from a feudal shogunate to the Meiji government. It is at end of Edo period and preceeded by Meiji era.
... vulva between the clitoris and the vaginal opening.
In the human male, the urethra is about 8 inches (200 mm) long and opens at the end of the penis.
Medical problems ...