The late Tokugawa shogunate or last shogun (幕末; Bakumatsu) is the period between 1853 and 1867 during which Japan ended its isolationist foreign policy and modernized from a feudal shogunate to the Meiji government. It is at end of Edo period and preceeded by Meiji era.
... County, Hawaii), he contracted the disease, from which he died at the colony.
He is the patron of lepers and outcasts, and was recently made the patron of AIDS patients. ...