Sertraline is used medically to treat the symptoms of depression. It is a selective serotonin reuptake inhibitors and works by blocking the uptake of serotonin into platelets. It is prescribed under the tradename Zoloft® and is manufactured by Pfizer, as white and yellow 50 mg capsules or orange 100 mg capsules. It is used in dosages of between 50 mg and a maximum of 200 mg per day. It has also been prescribed for the treatment of obsessive-compulsive disorder, post-traumatic stress disorder, premenstrual dysphoric mood disorder[?] and panic disorder[?]. It was first approved by the FDA in 1997.
It has a number of adverse effects including insomnia, asthenia, gastrintestinal complaints, tremours, confusion and dizziness, it can induce mania or hypomania in around 0.5% of patients. It is contraindicated in individuals taking MAOIs or undergoing electroconvulsive therapy.
Search Encyclopedia
|
Featured Article
|