Initial human symptoms are hypertension, fatigue and mild pain and urinary tract infections. The disease can lead to total loss of kidney function - End Stage Renal Disease[?] (ESRD).
The disease is both autosomal recessive and autosomal dominant. The recessive form, called ARPKD is the less common variant. The second type, called ADPKD or Adult Onset PKD is much more common.
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