Hybridization was the breeding of vinifera with resistant species. Native American grapes are naturally phylloxera resistant but have aromas that are offputting to palates accustomed to European grapes. The intent of the cross was to generate a hybrid vine that was resistant to phylloxera but produced wine that did not taste like the native grape. Ironically, the hybrids tend not to be especially resistant to Phylloxera, although they are much more hardy with respect to climate and other vine diseases. The new varieties have never gained the popularity of the traditional ones, and in the EU are generally banned or at least strongly discouraged from use in quality wine[?].
Use of a resistant rootstock involves grafting a vinifera scion[?] onto the roots of a resistant labrusca or other native species. This is the preferred method today, because the rootstock does not interfere with the development of the wine grapes, and it furthermore allows the customization of the rootstock to soil and weather conditions, as well as desired vigor. Unfortunately not all rootstocks are equally resistant. When phylloxera reached California, many growers used a rootstock called AXR-1 which was thought to be resistant. Sadly, it is not, and the replanting of afflicted vineyards continues today. Modern phylloxera infestation also occurs when wineries are in need of fruit immediately and cannot wait for grafted vines to be available.
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