Encyclopedia > Pancuronium bromide

  Article Content

Pancuronium bromide

Pancuronium bromide is a chemical compound, used in medicine with the brand name PavulonŽ (Organon Pharmaceuticals[?]).

It is a nondepolarizing medium-term muscle relaxant and works by curarimimetic action - the competitive antagonism with acetylcholine of the autonomic cholinergic receptors. Wtih the correct intravenous dosage the effects last around 45 minutes and it is used with general anaesthesia[?] in surgery for muscle relaxation and as an aid to intubation or ventilation. It does not have sedative[?] or analgesic effects.

Side effects include moderately raised heart rate[?] and thereby arterial pressure[?] and cardiac output, excessive salivation[?], apnea and respiratory depression[?], rashes[?], flushing and sweating[?]. The muscular relaxation can be dangerous in the seriously ill and it can accumulate leading to extended weakness.

Its empirical formula is:

C35H60Br2N2O 4

Its structural name is 3α, 17β - diacetoxy - 5α - androstan - 2β, 16β - ylene bis [1 - methylpiperidinium] dibromide



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
Wheatley Heights, New York

... of 2000, there are 5,013 people, 1,455 households, and 1,223 families residing in the town. The population density is 1,433.7/km² (3,704.7/mi²). There are ...

 
 
 
This page was created in 40.1 ms