Encyclopedia > Hyoscyamine

  Article Content

Hyoscyamine

Hyoscyamine is a chemical compound, a tropane[?] alkaloid it is the levo-isomer to atropine.

It is used in medicine under a number of brand names but also as a generic compund. It is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, IBS[?], pancreatitis, colic[?] and cystitis[?]. It has also been used to relieve some heart problems and control some of the symptoms of Parkinson's disease. It is anticholinergic[?], working by inhibting the action of acetylcholine in smooth and cardiac muscle, the sinoatrial and atrioventricular nodes and the exocrine glands.

Side effects include eye pain, blurred vision, restlessness, dizziness, arrythmia, flushing, faintness. An overdose will cause headache, nausea, vomiting and CNS symptoms including disorientation, hallucinations, euphoria, inappropriate affect, short-term memory loss and coma.

It can be extracted from plants of the Solanaceae family, notably Datura stramonium. Empirically it is C17H23NO3. Its structural name is α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-1αH,5αH-Tropan-3α-ol. It is also known as benzeneacetic acid.



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
East Islip, New York

... age of 18, 6.3% from 18 to 24, 32.3% from 25 to 44, 21.1% from 45 to 64, and 11.8% who are 65 years of age or older. The median age is 37 years. For every 100 females ...

 
 
 
This page was created in 26.2 ms