Encyclopedia > Calmodulin

  Article Content

Calmodulin

Calmodulin is a Ca2+-binding protein that is a key component of the Ca2+ second-messenger system and is involved in the regulation of many biochemical and physiological processes.

Calmodulin is a small, acidic protein approximately 148 amino acids long and, as such, is a favorite for testing protein simulation software. It is highly conserved across species, and its expression is essential for biological cells to progress through mitosis.

Calmodulin-stimulated protein phosphatase (EC 3.1.3.16) is the major calmodulin-binding protein in the brain.

Other calcium-binding proteins

Calmodulin belongs to one of the two main groups of calcium-binding proteins, called EF hand proteins. The other group, called annexins[?], bind calcium and phospholipid (e.g., lipocortin[?]). Many other proteins bind calcium, although binding calcium may not be considered their principal function in the cell.

External links

http://structbio.vanderbilt.edu/cabp_database/general/prot_pages/calmod



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
Westhampton Beach, New York

... 100 females there are 93.5 males. For every 100 females age 18 and over, there are 92.2 males. The median income for a household in the village is $58,438, and the median ...

 
 
 
This page was created in 37.1 ms