Acacius adviced the Byzantine emperor Zeno to issue the Henotikon edict[?] in 482, in which Nestorius and Eutyches were condemned, the twelve chapters of Cyril of Alexandria accepted, and the Chalcedon Definition ignored. This effort to shelve the Monophysites dispute was quite in vain. Pope Felix III saw the prestige of his see involved in this slighting of Chalcedon and his predecessor Leo’s epistle. He condemned and deposed Acacius, a proceeding which the latter regarded with contempt, but which involved a breach between the two sees that lasted after Acacius’s death through the long and troubled reign of emperor Anastasius I, and was only healed by Justin I in 519.
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