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456

Centuries: 4th century - 5th century - 6th century

Decades: 400s 410s 420s 430s 440s - 450s - 460s 470s 480s 490s 500s

Years: 451 452 453 454 455 - 456 - 457 458 459 460 461


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Heraclitus of Ephesus

... philosopher, disagreed with Thales, Anaximander, and Pythagoras about the nature of the ultimate substance. He claimed instead that everything is derived from the Greek ...