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Trepanation, also known as trephinning or trepanning is a form of surgery where a hole is cut into the skull.

Trepanation has been carried out for non-medical reasons, including religious and mystical practices. Some trepanation advocates believe the procedure to have spiritual benefits, but it is generally not carried out by doctors without a medical indication.

There is evidence of trepanation in pre-historic human remains. See also: Trephinning in pre-Columbian Mesoamerica

The operation is depicted in a painting by the artist Hieronymus Bosch entitled The Cure for Folly: Trepanning, alternatively entitled The Stone Operation.

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Thomas a Kempis

... Later he was admitted to the Augustinian convent of Mount Saint Agnes near Zwolle where his brother John had been before him and had risen to the dignity of prior. ...

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