Although its method of operation is not fully understood it is believed to work in two complementary ways: The parent molecule and the first metabolite[?] can bind to the nervous system opioid receptors[?], and cause the weak inhibition of norepinephrine and serotonin reuptake. The metabolite appears to be the stronger ligand in this.
Tramadol is sold under the following brand names:
Tramal, Ultram (more?)
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