Encyclopedia > Tramadol

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Tramadol is an analgesic, a synthetic analogue of codeine. It appears to have similar effects to opioids such as morphine, but is not addictive.

Although its method of operation is not fully understood it is believed to work in two complementary ways: The parent molecule and the first metabolite[?] can bind to the nervous system opioid receptors[?], and cause the weak inhibition of norepinephrine and serotonin reuptake. The metabolite appears to be the stronger ligand in this.

Brand names

Tramadol is sold under the following brand names:

Tramal, Ultram (more?)

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