Encyclopedia > Thyrotropin-releasing hormone

  Article Content

Thyrotropin-releasing hormone

Thyrotropin-releasing hormone (TRH) is a tripeptide hormone produced by the hypothalamus and stimulating production of TSH[?] and prolactin by the anterior lobe of the pituitary. It is passed from hypothalamus (eminentia mediana) to the pituitary by the means of the pituitary portal system. The sequence of TRH was first determined and the hormone was synthetised by Roger Guillemin[?] and Andrew V. Schally[?] in 1969. The presence of TRH can also be detected in other parts of the brain, in the gastrointestinal system and pancreatic islets. Medical preparations of TRH are used in diagnostic tests of thyroid disorders and in acromegly.

Structure : (pyro)Glu-His-Pro-NH2
Molecular weight : 359,5 D



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
Johann Karl Friedrich Rosenkranz

... formed the "centre," midway between Erdmann and Gabler on the one hand, and the "extreme left" represented by Strauss, Feuerbach and Bruno Bauer. Of his numerous ...

 
 
 
This page was created in 30.3 ms