Encyclopedia > Statin

  Article Content

Statin

The statins are a class of pharmaceuticals that act by competitively inhibiting 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase. The reductase is an enzyme involved in the liver cholesterol synthesis. The drugs are the most potent cholesterol lowering agents (LDL-cholesterol), however, they are less effective than the fibrates[?] in reducing triglycerides and raising HDL-cholesterol[?]. The statins play an important role in primary and secondary prevention of ischaemic heart disease and myocardial infarct.

There is ongoing research for other actions of statins apart from lipid-lowering for instance - anti-inflammatory or anti-dementive.

The statins are (brand names in coutries other than the US can be different):



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
Reformed churches

... periods of persecution scattered French Reformed refugees to England, Germany, Switzerland, Africa and America. A free (meaning, not state controlled) synod of th ...

 
 
 
This page was created in 24.7 ms