Encyclopedia > Spherocytosis

  Article Content

Spherocytosis

Spherocytosis is an anemia characterized by red blood cells that are sphere-shaped, rather than donut-shaped. Spherocytes are most commonly found in immunologically-mediated hemolytic anemias and in hereditary spherocytosis. The former would have a positive direct Coombs antibody test; the latter would not.

Hereditary spherocytosis is caused by a molecular defect in one of the proteins of the red blood cell cytoskeleton (usually ankyrin, sometimes spectrin). It is an autosomal dominant trait.



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
Islip Terrace, New York

... Geography Islip Terrace is located at 40°44'55" North, 73°11'11" West (40.748738, -73.186417)1. According to the United States Census Bureau, the town has ...

 
 
 
This page was created in 41.3 ms