Encyclopedia > Sodium thiopental

  Article Content

Sodium thiopental

Sodium thiopental, Also called sodium pentothal (TM of Abbott Laboratories), thiopental (or thiopentone) sodium.

5-ethyl-5-(1-methylbutyl)-2-thiobarbituric acid, C11H17O2N2NaS.

Short-acting barbiturate drug that induces brief general anesthesia (10-30 minutes) without analgesia by depression of CNS within 60 seconds of injection. Since analgesia is slight, thiopental is only used alone for brief procedures. It is more commonly used to induce hypnosis and anesthesia prior to the use of other anesthetic agents. It is also a a radioprotective agent and used in narcotherapy[?]. Along with pancuronium bromide and potassium chloride it is used in some States of the US as part of the lethal injection. In the past it was claimed as a truth drug.

Side effects include head ache, retrograde amnesia, emergence delirium, prolonged somnolence and nausea.

It was discovered in 1936 by Ernest H. Volwiler and Donalee L. Tabern, working for Abbott Laboratories.

All Wikipedia text is available under the terms of the GNU Free Documentation License

  Search Encyclopedia

Search over one million articles, find something about almost anything!
  Featured Article
Reformed churches

... Helvetic Confession[?] as a definition of their teaching, together the Ecumenical creeds of the Christian Church: Athanasian Creed, Nicene Creed, Chalcedon, and the common ...

This page was created in 31.8 ms