Since sequent calculi and the general concepts relating to them are of major importance to the whole field of proof theory and mathematical logic, the system LK will be explained in greater detail below. Some familarity with the basic notions of predicate logic (especially its syntactic structure) is assumed.

A (formal) proof in this calculus is a sequence of sequents, where each of the elements is derivable from a number of sequents, that appear earlier in the sequence, by using one of the below rules. An intuitive explanation of these rules is given thereafter. Please do also refer to sequent and rule of inference if you are not familiar with these concepts.
The Sequent calculus LK has been introduced by Gerhard Gentzen as a tool for studying natural deduction (which has been around before, although not quite as formal). It has subsequently turned out to be a much more easy to handle calculus when constructing logical derivations. The name itself is derived from the German term Logischer Kalkül, meaning logical calculus. Sequent calculi are the method of choice for many investigations on the subject.
The following notation will be used:
Axiom:  Cut:  
A  A 
(I) 
Γ  A, Δ Σ, A Π
Γ, Σ  Δ, Π 
(Cut)  
Left logical rules:  Right logical rules:  
Γ, A  Δ
Γ, A∧B  Δ 
(∧L_{1})  
Γ, B  Δ
Γ, A∧B  Δ 
(∧L_{2}) 
Γ  A, Δ
Σ  B, Π
Γ, Σ  A∧B, Δ, Π 
(∧R)  
Γ, A  Δ
Σ, B  Π
Γ, Σ, A∨B  Δ, Π 
(∨L) 
Γ  A, Δ
Γ  A∨B, Δ 
(∨R_{1})  
Γ  B, Δ
Γ  A∨B, Δ 
(∨R_{2})  
Γ  A, Δ
Σ, B  Π
Γ, Σ, A→B  Δ, Π 
(→L) 
Γ, A  B, Δ
Γ  A→B, Δ 
(→R)  
Γ  A, Δ
Γ, ¬A  Δ 
(¬L) 
Γ, A  Δ
Γ  ¬A, Δ 
(¬R)  
Γ, A[t]  Δ
Γ, ∀x A[x/t]  Δ 
(∀L) 
Γ  A[y], Δ
Γ  ∀x A[x/y], Δ 
(∀R)  
Γ, A[y]  Δ
Γ, ∃x A[x/y]  Δ 
(∃L) 
Γ  A[t], Δ
Γ  ∃x A[x/t], Δ 
(∃R)  
Left structural rules:  Right structural rules:  
Γ  Δ
Γ, A  Δ 
(WL) 
Γ  Δ
Γ  A, Δ 
(WR)  
Γ, A, A  Δ
Γ, A  Δ 
(CL) 
Γ  A, A, Δ
Γ  A, Δ 
(CR)  
Γ1, A, B, Γ2  Δ
Γ1, B, A, Γ2  Δ 
(PL) 
Γ  Δ1, A, B, Δ2
Γ  Δ1, B, A, Δ2 
(PR) 
Note: In the rules (∀R) and (∃L), the variable y must not be free within Γ, A[x/y], or Δ.
The above rules can be divided into two major groups: logical and structural ones. Each of the logical rules introduces a new logical formula either on the left or on the right of the turnstile . In contrast, the structural rules operate on the structure of the sequents, ignoring the exact shape of the formulae. The two exceptions to this general scheme are the axiom of identity (I) and the rule of (Cut).
Although stated in a formal way, the above rules alow for a very intuitive reading in terms of classical logic. Consider, for example, the rule (∧L_{1}). It says that, whenever one can prove that Δ can be concluded from some sequence of formulae that contain A, then one can also conclude Δ from the (stronger) assumption, that A∧B holds. Likewise, the rule (¬R) states that, if Γ and A suffice to conclude Δ, then from Γ alone one can either still conclude Δ or A must be false, i.e. ¬A holds. All the rules can be interpreted in this way.
For an intuition about the quantifier rules, consider the rule (∀R). Of course concluding that ∀x A[x/y] holds just from the fact that A[y] is true is not in general possible. If, however, the variable y is not mentioned elsewhere (i.e. it can still be chosen freely, without influencing the other formulae), then one may assume, that A[y] holds for any value of y. The other rules should then be pretty straightforward.
Instead of viewing the rules as descriptions for legal derivations in predicate logic, one may also consider them as instructions for the construction of a proof for a given statement. In this case the rules can be read bottomup. For example, (∧R) says that, in order to prove that A∧B follows from the assumptions Γ and Σ, it suffices to prove that A can be concluded from Γ and B can be concluded from Σ, respectively. Note that, given some antecedent, it is not clear how this is to be split into Γ and Σ. However, there are only finitely many possibilities to be checked since the antecedent by assumption is finite. This also illustrates how proof theory can be viewed as operating on proofs in a combinatorical fashion: given proofs for both A and B, one can construct a proof for A∧B.
When looking for some proof, most of the rules offer more or less direct recipes of how to do this. The rule of cut is different: It states that, when a formula A can be concluded and this formula may also serve as a premisse for concluding other statements, then the formula A can be "cut out" and the respective derivations are joined. When constructing a proof bootomup, this creates the problem of guessing A (since it does not appear at all below). This issue is addressed in the theorem of cutelimination[?].
The second rule, that is somewhat special, is the axiom of identity (I). The intuitive reading of this is obvious: A proves A.
Sequential derivation of (A∨¬A) to be included
The structural rules deserve some additional discussion. The names of the rules are Weakening (W), Contraction (C), and Permutation (P). Contraction and Permutation assure that neither the order (P) nor the multiplicity of occurrences (C) of elements of the sequences do matter. Thus, one could instead of sequences also consider sets.
The extra effort of using sequences, however, is justified since part or all of the structural rules may be omitted. Doing so, one obtains the so called substructural logics[?].
This system of rules can be shown to be both sound and complete with respect to firstorder logic, i.e. a statement A follows semantically from a set of premisses Γ (Γ = A) iff the sequent Γ  A can be derived by the above rules.
In Sequent calculus, the rule of cut is admissible[?]. This result is also referred to as Gentzen's Hauptsatz ("Main Theorem").
The above rules can be modified in various ways without changing the essence of the system LK. All of these modifications may still be called LK.
First of all, as mentioned above, the sequents can be viewed to consist of sets or multisets[?]. In this case, the rules for permuting and (when using sets) contracting formulae are obsolete.
The rule of weakening will become admissible, when the axiom (I) is changed, such that any sequent of the form Γ, A  A, Δ can be concluded. This means that A proves A in any context. Any weakening that appears in a derivation can then be performed right at the start. This may be a convenient change when constructing proofs bottomup.
Independent of these one may also change the way in which contexts are split within the rules: In the cases (∧R), (∨L), and (→L) the left context is somehow split into Γ and Σ when going upwards. Since contraction allows for the duplication of these, one may assume that the full context is used in both braches of the derivation. By doing this, one assures that no important premisses are lost in the wrong branch. Using weakening, the irrelevant parts of the context can be eliminated later.
All of these changes yield equivalent systems in the sense that every derivation in LK can effectively be transformed in a derivation using the alternative rules and vice versa.
Surprisingly, some small changes in the rules of LK suffice in order to turn it into a proof system for intuitionistic logic. To this end, one has to restrict to intuitionistic sequents (i.e. the right contexts are eliminated) and modify the rule (∨L) as follows:
Γ, A  C Σ, B C
Γ, Σ, A∨B  C 
(∨Li) 
The resulting system is called LJ. It is sound and complete with respect to intuitionistic logic and admits a similar cutelimination proof.
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