To act in one's self-interest is to act mainly for ones own good, loving what is one's own (ego, body, family, house, belongings in general). It means to give one's own interests higher priority then others'.
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... The racial makeup of the town is 74.50% White, 11.00% African American, 1.00% Native American, 1.88% Asian, 0.00% Pacific Islander, 7.00% from other races, and 4.62% ...