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Paternity testing

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A paternity test is conducted to prove that a man is or is not the biological father of another individual. This may be relevant in view of rights and duties of the father. Similarly a maternity test can be carried out. This is less common because at least during birth it is obvious who the mother is.

This can be achieved by DNA analysis[?] of the two individuals.

The DNA of an individual is almost exactly the same in each and every cell of that individual. This genetic material is determined from the genetic material of both his father and mother. Sexual reproduction involves shuffling the DNA of both the father and the mother and then brining them together in a cell that have its own unique genetic material. So the genetic material of an individual is basically derived from the genetic material of the parents of that individual. This genetic material is known as the nuclear genome[?] of the individual, because it is found in the nucleus.

Comparing the DNA sequence of an individual to that of another individual can show if one of them was derived from the other or not. Specfic sequences are usually looked at to see if they were copied verbatim from one of the individuals genome to the other. If that was the case, then this proves that the genetic material of one individual was derived from that of the other (i.e.: one is the parent of the other). This way, paternity can be proved or denied.

Besides the nuclear DNA in the nucleus, the mitochondria in the cells also have their own genetic material termed the mitochondrial genome. The mitochondrial genetic material is much less in contenet than the nuclear genetic material and comes 'only from the mother' and without any shuffling.

Proving parenthood based on the mitochondrial genome is much easier than that based on the nuclear genome[?]. However, testing the mitochondrial genome can only prove if an individual is the mother of another, not for proving a father.

External link

  • Recovering the Romanovs (http://www.dnai.org/romanovs/): an interactive website showing how mitochondrial DNA comparison was used as a maternity test in a very interesting case.



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