Encyclopedia > Myoglobin

  Article Content


Myoglobin (oxy-myoglobin at 1.0 Angstrom resolution: PDB 1A6M (http://www.rcsb.org/pdb/cgi/explore.cgi?pid=105291034356398&page=0&pdbId=1A6M). Sperm whale myoglobin at 1.7 Angstrom resolution: PDB 1VXH (http://www.rcsb.org/pdb/cgi/explore.cgi?pid=255731034609024&page=80&pdbId=1VXH)) is a single-chain protein of 153 amino acids, containing an iron porphyrin group in the center and being the primary oxygen-carrying pigment of muscle tissues. Unlike hemoglobin, to which it is structurally related, this protein does not exhibit cooperative binding of oxygen. Instead, the binding of oxygen by myoglobin is unaffected by the oxygen tension in the surrounding tissue. In 1957, John Kendrew[?] and associates successfully determined the structure of myoglobin by high-resolution X-ray crystallography.

For this, in 1962, John Kendrew shared the Nobel Prize in chemistry with Max Perutz.

See also hemoglobin, hemoprotein

All Wikipedia text is available under the terms of the GNU Free Documentation License

  Search Encyclopedia

Search over one million articles, find something about almost anything!
  Featured Article
Wheatley Heights, New York

... householder with no husband present, and 15.9% are non-families. 13.0% of all households are made up of individuals and 5.2% have someone living alone who is 65 years ...

This page was created in 36.2 ms