Moonraker

In Moonraker (1979), James Bond reaches the villain's orbital lair by means of the Space shuttle (which was soon to be launched for real when the movie was released). Widely considered to be one of the most juvenile Bond movies, it is, (oddly?) perhaps the least sexist. The "Bond girl" is a CIA agent who competently wards off bad guys and pilots the space shuttle. And sleeps with Bond.