Encyclopedia > Ligase

  Article Content

Ligase

A Ligase is an enzyme that can ligate[?] ("glue together") two molecules with a covalent bond, using energy from ATP.

DNA ligase can ligate broken DNA strands, forming covalent phosphodiester bonds.

An example of how a ligase works (with sticky ends):

 5'-AGTCTGATCTGACT        GATGCGTATGCTAGTGCT-3'
 3'-TCAGACTAGACTGACTACG        CATACGATCACGA-5'
 becomes
 5'-AGTCTGATCTGACTGATGCGTATGCTAGTGCT-3'
 3'-TCAGACTAGACTGACTACGCATACGATCACGA-5'



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
Islandia, New York

... every 100 females there are 92.3 males. For every 100 females age 18 and over, there are 88.8 males. The median income for a household in the village is $69,519, and ...

 
 
 
This page was created in 24.3 ms