An instrument is a concrete or abstract tool intended for a purpose other than mechanical work, in particular a refined one.
Musical instruments are devices designed to produce music, frequently by plucking or striking a string or bell or drum surface, or by forcing air to resonate (see wind instruments).
... in Italy.
1524 to 6 saw the Peasants' Revolt in Germany and the formation of the Lutheran Schmalkaldic League, and Charles delegated increasing responsibility for ...