An instrument is a concrete or abstract tool intended for a purpose other than mechanical work, in particular a refined one.
Musical instruments are devices designed to produce music, frequently by plucking or striking a string or bell or drum surface, or by forcing air to resonate (see wind instruments).
... He was the son of Philip I and Joanna of Castile and grandson of Ferdinand II of Aragon and Isabella I of Castile and of Maximilian I, Holy Roman Emperor.
Charles ...