Drugs used include barbiturates, benzodiazepines, cyclopyrrolone[?], chloral hydrate[?], chlormethiazole[?] or the antihistamines[?] promethazine and diphenhydramine.
... Jerónimo de Yuste[?], Spain September 21, 1558) was Holy Roman Emperor (as Charles V) from 1519-1558; he was also King of Spain from 1516-1556 -- officially as Charles I ...