Fluoxetine has a wide range of interactions, notably with monoamine oxidase inhibitors. Common side-effects include anxiety, restlessness, trembling, weakness, skin rash, itching and a decrease in sexual drive.
Fluoxetine was introduced in the US in 1987 and was initially very popular, over a million Americans were prescibed the drug a year. In the late 1990s there was something of a backlash with accusations that the drug made users feel suicidal and other serious side effects.
There is a lot of controversy surrounding Eli Lilly and Company, the producent of Prozac. A class action lawsuit has been filed recently against Eli Lilly after several people received free samples of Prozac Weekly in the mail.
The controversial Prozac approval process described, as well as side effects of other SSRIs and other types of medication, can be found on Prozac Truth, The Untold Story website.
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