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Coxsackie A

Coxsackie A is a cytolytic virus of the Picornaviridae[?] family, a enterovirus[?] (a group containing the polioviruses[?], coxsackieviruses, and echoviruses[?]). There are 61 non-polio enteroviruses that can cause disease in humans, of them 23 are Coxsackie A viruses (6 are Coxsackie B[?] viruses). Enterovirus are the second most common viral infectious agents in humans (after the rhinoviruses)

The most well known Coxsackie A disease is Hand-Foot-and-Mouth Disease[?] (unrelated to Foot-and-Mouth Disease), a common childhood illness, often produced by Coxsackie A16. In most cases infection is asymptomatic[?] or causes only mild symptoms. In others, infection produces short-lived (7-10 days) fever and painful blisters[?] in the mouth, on the palms and fingers of the hand, or on the soles of the feet.

Other diseases include acute haemorrhagic conjunctivitis (A24 specifically), herpangina[?], and aseptic meningitis (both Coxsackie A and B viruses).

Coxsackie B viruses also cause infectious myocarditis[?], infectious pericarditis[?], and pleurodynia[?].

see also Bornholm disease



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