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In genetics, a double-dtranded DNA or RNA strand consists of two complementary strands of base pairs, which are non-covalently connected via two or three hydrogen bonds.

Since there is only one complementary base for any of the bases found in DNA/RNA, one can reconstruct a complementary strand for any single strand. This is essential for DNA replication.

For example, the complementary strand of the DNA sequence

 A G T C A T G
 T C A G T A C

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... contents runs as follows: Introduction Looking Ahead: Tenth Anniversary Interview (an interview conducted ten years since Barsamian first interviewed Chomsky) ...

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