Encyclopedia > Bacterial artificial chromosome

  Article Content

Bacterial artificial chromosome

A Bacterial Artificial Chromosome (or BAC) is a vector, based on a fertility plasmid, used for cloning in bacteria, usually E. coli. Its usual insert size is 150 kbp, with a range from 100 to 300 kbp.

BACs are often used in sequencing other organisms, in genome projects[?], for example the Human Genome Project. A short piece of the organisms DNA is amplified as an insert in BACs, then sequenced. Finally, the sequenced parts are rearranged in silico[?], resulting in the genome sequence of the sequenced organism.



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
1904

... actor July 12 - Deng Xiaoping, Chinese politician and leader July 13 - Pablo Neruda, poet August 28 - Secondo Campini, Italian jet pioneer November 30 - Clyfford ...

 
 
 
This page was created in 37.1 ms