The full title of the first edition, The Anatomy of Melancholy, What it is: With all the Kinds, Causes, Symptomes, Prognostickes, and Several Cures of it. In Three Maine Partitions with their several Sections, Members, and Subsections. Philosophically, Historically, Opened and Cut up. In contemporary language, an Anatomy of Melancholy would likelier be called A Treatise on Clinical Depression. At the outset, then, Burton proposes to give us a medical textbook. And in large measure, that is what it is: Burton applies his large and varied learning in the Scholastic manner to the subject of melancholia. Each section piles on ancient and mediæval medical authorities, from Hippocrates, Aristotle and Galen forward, and adds to these ancient examples a great deal of Latin poetry. Burton defines his subject this way:
So far, it seems an unlikely candidate for a book with lasting literary value. But Burton is unable to prevent his attention from wandering, and his digressions are the reader's gain. He opens with a long address titled Democritus Junior to the Reader, in which he confesses his personal predisposition to melancholia. So his writing this book was as much a self-diagnosis and self-therapy as it was an endeavour to inform. Psychology, physiology, astronomy, astrology, demonology, meteorology, and theology are all pressed into service to elucidate his topic, which is no less than a catalogue of the various sorrows and frustrations that human beings are heir to.
Noteworthy sections besides Democritus Junior to the Reader are his discourses on the melancholy of scholars, the melancholy of lovers, and his counsels as to how one can fall out of love. And in the midst of all of this, he also finds the place to propose his own Utopia. The Anatomy of Melancholy has been admired by many subsequent writers, from Samuel Johnson and Charles Lamb to Stanley Fish.
The Complete Review discussion of The Anatomy of Melancholy can be read here: http://www.complete-review.com/reviews/divphil/burtonr.htm
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