Encyclopedia > Amide hydrolysis

Article Content

Amide hydrolysis

Amide hydrolysis involves the C-N bond being broken in reaction with water (hydrolysis). The reaction is catalysed by either acid or alkali.

Procedure:

The amide is heated under reflux with moderately concentrated acqueous acid or alkali. If an acid is used, the product contains Ammonia ions. If a alkali is used, the carboxylic acid loses an H⁺ ion and the product contains carboxylate ions.

All Wikipedia text is available under the terms of the GNU Free Documentation License

Search Encyclopedia

Search over one million articles, find something about almost anything!

Featured Article

Charles V, Holy Roman Emperor

... to gain him some respite from the huge expenses of their war. In 1545 the opening of the Council of Trent began the Counter-Reformation, and Charles won to the Catholi ...