, also known as AMP
, is the product of adenosine
condensation with a single phosphate
AMP can be produced during ATP synthesis by the enzyme adenylate kinase[?] by combining two ADP molecules:
- 2 ADP → ATP + AMP
Or AMP may be produced by the hydrolysis of one high energy phosphate bond of ADP:
- ADP → AMP + Pi
AMP can also be formed by hydrolysis of ATP into AMP and pyrophosphate:
- ATP → AMP + PPi
When RNA is broken down by living systems, nucleoside monophosphates, including adenosine monophosphate, are formed.
AMP can be regenerated to ATP as follows:
- AMP + ATP → 2 ADP (adenylate kinase in the opposite direction)
- 2 ADP + 2 Pi → 2 ATP (this step is most often performed in aerobes by the ATP synthase during oxidative phosphorylation)
AMP can be converted into IMP[?] by the enzyme myoadenylate deaminase[?], freeing an ammonia group.
In a catabolic pathway, adenosine monophosphate can be converted to uric acid, which is excreted from the body.
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