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Alkylating agent

Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. They stop tumour growth by cross-linking guanine bases in DNA double-helix strands - directly attacking DNA. This makes the strands unable to uncoil and separate. As this is necessary in DNA replication, the cells can no longer divide.



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1904

... 26 - Ancel Keys, scientist February 1 - S. J. Perelman[?], humorist, author February 4 - MacKinlay Kantor[?], historian (+ 1977) February 5 - Walter Gross[?], ...

 
 
 
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