Encyclopedia > Aconitine

  Article Content

Aconitine

Aconitine is a highly poisonous alkaloid derived from the aconite plant. It is a neurotoxin[?] that opens TTX-sensitive Na+ channels in the heart and other tissues, and is used for creating models of cardiac arrhythmia.

Aconitine has the chemical formula C34H47NO11, and is soluble in chloroform or benzene, slightly in alcohol or ether, and practically not at all in water. It has an LD50 in mice (intravenously) of 0.12 mg/kg and in rats (orally) of 5.97 mg/kg.



All Wikipedia text is available under the terms of the GNU Free Documentation License

 
  Search Encyclopedia

Search over one million articles, find something about almost anything!
 
 
  
  Featured Article
BBC News 24

... the BBC's 24-hour news television channel. It first broadcast in November 1997 and at first only cable television subscribers could view it. In 1999, with the advent of ...

 
 
 
This page was created in 33.1 ms